Multimodal imaging (MMI) has transitioned from a supportive role to a central pillar in the early diagnosis of Vogt-Koyanagi-Harada (VKH) disease because it can detect subclinical inflammation that is often…
1. Overview of the Review This systematic review and meta‑analysis synthesized 63 studies involving 7316 participants. It evaluated how CVI differs across 12 physiological and disease conditions, using OCT‑derived measurements.…
Differentiating Purtscher flecken from cotton-wool spots (also called soft exudates) is primarily done on fundus examination (clinical appearance), with OCT providing supportive but often overlapping information in the acute phase.…
Clinical Research Update Tirzepatide and Reduced Risk of Diabetic Retinopathy and Related Complications: A Multicenter U.S. Cohort Study Ophthalmology, 2026 • PMID: 41577258 Objective & Study Design This population-based, retrospective…
IntroductionMacular telangiectasia (MacTel) is an insidious neurodegenerative disorder with a characteristic angiographic pattern and localized manifestations. It belongs to a heterogeneous group of rare disorders that characteristically involve the perifoveal…
Introduction Dome-shaped macula (DSM), first described in 2008, has evolved from an imaging curiosity to a recognized clinical entity with significant implications for retinal practice. Once thought to occur exclusively…
Retinal Cavernous Hemangioma Quiz Retinal Cavernous Hemangioma Quiz Test your knowledge of retinal cavernous hemangioma based on the provided medical content. Select your answer for each question and see immediate…
Introduction: A New Look at a Complex Disease Autosomal Recessive Bestrophinopathy (ARB) is known for its wide clinical and genetic variability, making it a particularly challenging inherited retinal disease to…
Pilocarpine for Presbyopia: A Meta-Analysis of Short-Term Efficacy and Safety – Implications for Vitreoretinal Practice IntroductionAs vitreoretinal surgeons, we are keenly aware of the delicate balance between therapeutic innovation and…
Topic: Subretinal Hyperreflective Material, Atrophy, and Intraretinal Fluid in Pachychoroid Neovasculopathy (PNV)Reference: Baek J, Ra H, Lee SH, Cheung CMG, Lee WK. Am J Ophthalmol. 2025;280:472–480. Key Findings at a Glance A recent…
For decades, we’ve approached central serous chorioretinopathy (CSCR) through the lens of choroidal hyperpermeability, pachychoroid, and venous congestion. But what if a fundamental, routinely measured clinical parameter has been quietly…
Advanced imaging, particularly swept-source optical coherence tomography angiography (SS-OCTA), continues to refine our understanding of retinal microanatomy and disease pathophysiology. Two recent publications shed light on the structural and vascular…
Rethinking NPDR: From a Single Pathway to Three Distinct Phenotypes As vitreoretinal surgeons, we recognize that not all patients with nonproliferative diabetic retinopathy (NPDR) progress to vision-threatening complications. A groundbreaking…
Key Findings from a Large Retrospective Study (2014–2018) As vitreoretinal surgeons, we are often called upon to manage complications arising from cataract surgery, with posterior capsular rupture (PCR) being one…
Key Takeaway: Peripheral laser photocoagulation for retinal degeneration does not significantly increase the risk of epiretinal membrane (ERM) formation, but certain treatment parameters might. Prophylactic laser treatment for peripheral retinal degeneration is a…
Hemoglobin and DR Quiz Hemoglobin and Diabetic Retinopathy: Test Your Knowledge 1 What was the strongest association found between low hemoglobin levels and diabetic retinopathy (DR) in the reviewed study?…
Vitreous hemorrhage (VH) is a common but alarming condition where blood leaks into the vitreous cavity, often causing a sudden and painless loss of vision. While it affects approximately 7…
SORVL Quiz SORVL Quiz 1. What is the reported incidence range of silicone oil removal–related vision loss (SORVL)? 40–60% 1–33% 70–90% 0.1–1% 2. Which mechanism has been proposed to explain…