Farabi Retina

This research highlights the connection between retinal ischemic perivascular lesions (RIPLs), observed through noninvasive eye imaging (OCT/OCTA), and single subcortical infarction (SSI), a type of stroke. The study found that the presence of RIPLs is independently associated with SSI and correlates with a higher burden of cerebral small vessel disease in SSI patients, including increased white matter lesions and enlarged perivascular spaces in the brain. Additionally, eyes with RIPLs showed lower blood vessel density in a specific layer of the retina. These findings suggest that RIPLs could serve as a readily detectable marker of both retinal and cerebral ischemia, potentially aiding in the early identification of individuals at risk for or affected by small vessel disease in the brain.