Retinal ischemic perivascular lesions (RIPLs) are linked to single subcortical infarction (SSI)

  • 🔍 Retinal ischemic perivascular lesions (RIPLs) are linked to single subcortical infarction (SSI) independent of risk factors (OR 1.506, P<0.001).
  • 🧠 RIPLs correlate with increased cerebral small vessel disease (SVD) burden in SSI patients, including higher periventricular white matter hyperintensity (PWMH) and perivascular spaces in basal ganglia (PVS-BG).
  • 🖥️ Eyes with RIPLs exhibit lower density in the deep vascular complex (DVC) compared to those without RIPLs in SSI.
  • 🏥 RIPLs could serve as an additional marker for cerebral ischemic changes detectable via noninvasive optical coherence tomography (OCT/OCTA).
  • 🔄 RIPLs are anatomical indicators of retinal ischemia.
  • 🧠 RIPLs may indicate early evidence of retinal and cerebral ischemia in SSI.
  • 🩸 RIPLs correlate with lower DVC density in SSI patients.
  • 💡 RIPLs are linked with increased burden of PWMH in cerebral SVD.
  • 🧬 RIPLs are associated with increased PVS-BG burden in SSI patients.
  • Reference:
  • https://www.ahajournals.org/doi/10.1161/JAHA.123.033081

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